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What is the difference between Spravato nasal ketamine, intramuscular ketamine, and IV ketamine?


Spravato, intramuscular ketamine, and IV ketamine are all forms of the medication ketamine, but they differ in how they are administered and their potential uses.


Spravato is a nasal spray form of ketamine that is FDA-approved for the treatment of depression and treatment-resistant depression. It is administered under the supervision of a healthcare provider and must be taken in a certified medical office.


Intramuscular ketamine is a form of medication that is injected into a muscle. It is commonly used as a general anesthetic in surgical procedures and can also be used off-label for the treatment of chronic pain and depression.


IV ketamine, also known as intravenous ketamine, is a form of medication injected directly into a vein. It is commonly used as a general anesthetic in surgical procedures and can also be used off-label for the treatment of chronic pain, depression, and other conditions.


One key difference between these forms of ketamine is their potential uses. While both intramuscular and IV ketamine can be used off-label for the treatment of chronic pain and depression, only Spravato has been FDA-approved for the treatment of depression and treatment-resistant depression.


Another difference is the method of administration. Spravato is administered as a nasal spray, while intramuscular and IV ketamine is injected into a muscle or vein, respectively. This can affect the speed at which the medication takes effect and the potential side effects.


Overall, while all forms of ketamine are derived from the same medication, they differ in their potential uses and administration methods. It is essential to consult with a healthcare provider to determine the best form of ketamine for your individual needs

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